Pretreatment with or concurrent administration of phenobarbital may decrease the impact of estradiol by expanding its metabolism.
butabarbital will lessen the level or outcome of paclitaxel protein sure by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unfamiliar.
Documentation of allergenic cross-reactivity for barbiturates is proscribed. Nonetheless, on account of similarities in chemical framework and/or pharmacologic steps, the possibility of cross-sensitivity can not be ruled out with certainty.
butabarbital will lessen the extent or outcome of tamoxifen by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Monitor.
One particular limitation of this circumstance is always that Increased elimination methods, like hemodialysis may perhaps happen to be helpful in reducing some time to return of brainstem reflexes and the period of intubation, specifically in the context of a huge ingestion.
butabarbital will minimize the level or result of pitolisant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Pitolisant exposure is reduced by fifty% if coadministered with strong CYP3A4 inducers.
butabarbital will lessen get more info the extent or outcome of eletriptan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
butabarbital will lower the extent or effect of solifenacin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
butabarbital will reduce the extent or outcome of vincristine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unfamiliar.
butabarbital will minimize the extent or effect of isradipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unknown.
This medication may possibly induce accidental overdose and Dying if taken by other Grownups, children, or Animals. Mix any unused medicine which has a substance like cat litter or espresso grounds.
Some clients have necessary health care therapy during the unexpected emergency Section. If angioedema involves the tongue, glottis or larynx, airway obstruction may well arise and become lethal. Individuals who establish angioedema soon after therapy with sedative-hypnotics shouldn't be rechallenged Using the drug.
butabarbital will reduce the extent or impact of methylprednisolone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
MAOI extend the effects of barbiturates possibly because metabolism of the barbiturate is inhibited.